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"Musings on MeSH" reported Amar-Zifkin et al concluded that 47 % of records had minor or significant MeSH problems, which would indeed impact retrieval. Still relying exclusively on human indexing is no longer useful, and continuous improvement of the algorithm underscores NLM's commitment to precision. Extra (Spurious) MeSH Terms (Incorrect Positives) Askin et al., in their JMLA article "Filtering failure: the impact of automatic indexing in Medline on retrieval of human research studies for understanding synthesis," stated that indexing frequently consists of unimportant terms or omits clearly relevant ones re: human studies.
Chen et al. (2023) noted a frequent abuse or omission of check tags (e.g., gender or age). - mistakes in publication types were often hierarchically associated e.g., tagging as Historic Short article rather of more precise Biography, or Clinical Trial when it's a Clinical Study. PT errors impact search accuracy and filtering in search filters and understanding synthesis.
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Amar-Zifkin et al.

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"Musings on MeSH" blog states blog site automated indexing is based only on title and abstract, meaning details suggesting information in full textsuch as population descriptors or methodologycan be missed. Chen et al. stated the MTI tended to rank "Male" check tag more highly than "Female," and often omitted "Aged" check tagreflecting how terms can be missed.